Arthritis & Joint Pain

“Artho” and “itis” are the two greek words from which the term Arthritis has been derived, meaning joint and inflammation, respectively. Arthritis is a kind of joint disorder characterized by chronic inflammation in one or more joints that usually results in pain and is often disabling. Arthritis is of more than 100 different forms but the most common forms are osteoarthritis and rheumatoid arthritis. Arthritis is associated with pain and inflammation but the exact cause still remains uncertain and no treatment is available for its fundamental causes. Currently, drugs like analgesics, steroids, and nonsteroidal anti-inflammatory are given to arthritis patients which help in reduction of pain and inflammation. However, they cannot be used for long term due to inadequate pain relief, immune disturbances, and serious gastrointestinal and cardiovascular adverse events. Therefore, herbal therapies are needed with anti-inflammatory properties and minimal side effects. Curcumin, a Turmeric extract, is therefore believed to be the alternative medicine for arthritis. Curcumin do not modulate COX-1 activity, but modify NF-κB signaling, pro inflammatory cytokines such as interleukin production and phospholipase A2, COX-2, and 5-LOX activities. Curcumin also modulates the expressions of various transcription factors involved in energy metabolism such as signal transducer and activator of transcription, peroxisome proliferator-activated receptor-γ, and activator protein-1, cAMP responding element binding protein, estrogen response element, and others. As a result, turmeric and its components have been reported to exert beneficial effects on osteoarthritis.

Low Immunity

Natural defence by our body against disease causing bacteria and virus is called immunity. Our immune system fights such bacteria everyday. Strong immune system can reduce the odds of getting sick. Healthy diet, exercise, good sleep help in developing a good immune system. But, today’s fast moving life has led to the consumption of fast food and weird sleeping schedule. Instead of boosting our immunity we are actually dropping it.

Curcumin, the most active ingredient of turmeric, has anti-inflammatory, antioxidant, and antiviral impact on health. Researchers have shown that curcumin can triple the ammunition used by the body’s front-line immune cells to combat bacterial, viral, and fungal infection. It boosts the functionality of a molecule called Cathelicidin (Cathelicidin Anthimicrobial Peptide – CAMP). CAMP is the component present in the immune system which helps in the identification and eradication of bacteria and other unfamiliar external agents that attack and negatively impact the human body. Curcumin increases the CAMP activity and improves the body’s defense system against bacterial, viral and fungal infections.

Anti-ageing

An inevitable process of life is Ageing. Since ageing cannot be avoided, one can opt for healthy ageing. Wrinkles, sagging skin, age spots, hyperpigmentation are some of the signs of ageing. Wrinkles, skin sagging usually occur due to loss of collagen (a structural tissue that maintains a firm tissue), loss of fat tissue and gravitational force acting upon skin. The best solution for this is eating a diet, rich in anti-oxidants. Curcumin, an extract from turmeric, is strong anti-oxidants. Curcumin has antioxidant activity like vitamin C and E. Therefore, it is known to treat the oxidative stress conditions. It raises the level of antioxidants enzymes, scavenges free radicals (that cause oxidative stress) and inhibit lipid peroxidation (oxidation of fats present in the cell membrane leading to cell death). So, curcumin, with its powerful antioxidant property can help in delaying signs of ageing. It can also help in skin protection from UV damage which is a common cause of skin issues.

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Blood Purifier

Curcumin is one of the best natural blood purifiers. Curcumin removes accumulation of cholesterol in lever. The anticholesterol action means reducing intestinal cholesterol uptake, increasing the conversion of cholesterol into bile acids, and increasing the excretion of bile acids. curcumin reduces arterial plaque. Since it inhibits platelet aggregation, it can help circulation in many ways, including reducing the accumulation of deposits on arterial walls. A studies shows that it reduces smooth muscle damage in the artery, the beginning step in atherosclerosis (hardening of the arteries). Curcumin would wisely be used in artery disease or in recovery from bypass surgery or angioplasty. Anemia benefits from curcumin, as it facilitates the production of new blood cells. Its unique combination of characteristics makes it suitable in the treatment of varicose veins.

Anti-Oxidant

curcumin have also been considered to be associated with its antioxidant property. The main reason of antioxidants being so beneficial is that they protect our body from free radicals. Curcumin is a potent antioxidant that can neutralize free radicals because of its chemical structure. In addition, curcumin boosts the activity of our body's own antioxidant enzymes. In that way, curcumin delivers a 2 benefits against free radicals. It blocks them directly, then stimulates our body's own antioxidant defenses.

Anti-inflammatory

Turmeric curcumin is a wonderful anti-inflammatory agent. It’s a bioactive substance that fights inflammation at molecular level. It has been proved to be more effective than various anti-inflammatory drugs available in the market. When used orally, curcumin has many direct anti-inflammatory effects, which includes inhibiting leukotriene formation, inhibiting blood platelet aggregation, promotion of fibrinolysis, and stabilizing lysosomal membranes. The herb is wide employed for all joint conditions, and is said to have a general joint rebuilding capability. It is used in rheumatoid arthritis and gout (both internally and as a pack on the joint). It normalizes ligaments, and so facilitates stretching exercise, like Yoga.

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